1,725 research outputs found
Vocabulary and reading comprehension : instructional effects
Bibliography: leaves 32-34Supported by the National Institute of Educatio
Recommended from our members
A basic communications curriculum model for collegiate students with marginal and/or varying degrees of learning skills competency.
Endothelial preconditioning by transient oxidative stress reduces inflammatory responses of cultured endothelial cells to TNF-α
Brief episodes of ischemia can render an organ resistant to subsequent severe ischemia. This ‘ischemic preconditioning’ is ascribed to various mechanisms, including oxidative stress. We investigated whether preconditioning exists on an endothelial level. Human umbilical vein endothelial cells (HUVECs) were transiently confronted with oxidative stress (1 mM H2O2, 5 min). Adhesion molecules ICAM-1 and E-selectin and release of cytokines IL-6 and IL-8 to subsequent stimulation with TNF-α (2.5 ng/ml, 4 h) were measured (flow cytometry and immunoassay), as were nuclear translocation of the transcription factor NFkB (Western blotting, confocal microscopy) and redox status of HUVECs (quantification of glutathione by HPLC). TNF-α elevated IL-6 in the cell supernatant from 8.8 ± 1 to 41 ± 3 pg/ml and IL-8 from 0.5 ± 0.03 to 3 ± 0.2 ng/ml. ICAM-1 was increased threefold and E-selectin rose eightfold. Oxidative stress (decrease of glutathione by 50%) reduced post-TNF-α levels of IL-6 to 14 ± 3 and IL-8 to 1 ± 0.2; the rise of ICAM-1 was completely blocked and E-selectin was only doubled. The anti-inflammatory effects of preconditioning via oxidative stress were paralleled by reduction of the translocation of NFkB on stimulation with TNF-α, and antagonized by the intracellular radical scavenger N-acetylcysteine. ‘Anti-inflammatory preconditioning’ of endothelial cells by oxidative stress may account for the inhibitory effects of preconditioning on leukocyte adhesion in vivo
Photonic Band Gaps in 3D Network Structures with Short-range Order
We present a systematic study of photonic band gaps (PBGs) in
three-dimensional (3D) photonic amorphous structures (PAS) with short-range
order. From calculations of the density of optical states (DOS) for PAS with
different topologies, we find that tetrahedrally connected dielectric networks
produce the largest isotropic PBGs. Local uniformity and tetrahedral order are
essential to the formation of PBGs in PAS, in addition to short-range geometric
order. This work demonstrates that it is possible to create broad, isotropic
PBGs for vector light fields in 3D PAS without long-range order.Comment: 6 pages, 8 figure
Mixing-Demixing transition in 1D boson-fermion mixture at low fermion densities
We numerically investigated the mixing-demixing transition of the
boson-fermion mixture on a 1D lattice at an incommensurate filling with the
fermion density being kept below the boson density. The phase diagram we
obtained suggested that the decrease of the number of the fermions drove the
system into the demixing phase
- …